Comparison of effects on macrophage cultures of glass fibre, glass powder, and chrysotile asbestos.
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چکیده
منابع مشابه
Comparison of effects of glass fibre and glass powder on guinea-pig lungs.
Botham, Susan K., and Holt, P. F. (1973). British Journal ofIndustrial Medicine, 30, 232-236. Comparison of effects of glass fibre and glass powder on guinea-pig lungs. Following 24 hours inhalation by guinea-pigs of powdered glass dust, the pulmonary effects over the succeeding month differed from those previously observed to follow inhalation of glass fibre in that (1) fewer erythrocytes esca...
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Samples of rockwool and glass fibre were compared with chrysotile fibres for their capacity to hydroxylate 2-deoxyguanosine to 8-hydroxydeoxyguanosine, a reaction that is mediated by formation of hydroxyl radicals. All three fibres produced 8-hydroxydeoxyguanosine in the absence of H2O2. The chrysotile fibres were most potent and produced about ten times more of the modified nucleoside than roc...
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A number of studies have indicated that the relative toxicity of different fibre types after inhalation is related to their durability within lung tissue. The aim of this study was to assess the relative biopersistence of respirable para-aramid fibrils, chrysotile asbestos and code 100/475 glass fibres in rat lungs. The biopersistence of all three test fibres was measured by quantifying the cha...
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UICC, other well-defined asbestos samples and different man-made mineral fibers (MMM) such as glass fiber and synthetic amphibole asbestos were studied in vitro by using rat and guinea pig lung macrophages. These samples had relatively narrow length and diameter spectra. Most of the fiber samples were added to the cultures on a gravimetric basis, although some were added on a numerical basis. E...
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In an editorial entitled 'Fiber carcinogenesis: is asbestos the only hazard?', Stanton (1974) drew attention to the possibility that inhaled fibres other than asbestos, and in particular glass fibres, could be carcinogenic to humans. The hypothesis was based on experiments carried out on rats. Specially-bred experimental animals were subjected to intrapleural application of large numbers of spe...
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ورودعنوان ژورنال:
- British journal of industrial medicine
دوره 29 3 شماره
صفحات -
تاریخ انتشار 1972